Platelet chemokines in health and disease

E Karshovska, C Weber… - Thrombosis and …, 2013 - thieme-connect.com
E Karshovska, C Weber, P von Hundelshausen
Thrombosis and haemostasis, 2013thieme-connect.com
In recent years, it has become clear that platelets and platelet-derived chemokines, beyond
their role in thrombosis and haemostasis, are important mediators affecting a broad
spectrum of (patho) physiological conditions. These biologically active proteins are released
from α-granules upon platelet activation, most probably even during physiological
conditions. In this review, we give a concise overview and an update on the current
understanding of platelet-derived chemokines in a context of health and disease. Note: The …
In recent years, it has become clear that platelets and platelet-derived chemokines, beyond their role in thrombosis and haemostasis, are important mediators affecting a broad spectrum of (patho)physiological conditions. These biologically active proteins are released from α-granules upon platelet activation, most probably even during physiological conditions. In this review, we give a concise overview and an update on the current understanding of platelet-derived chemokines in a context of health and disease.
Note: The review process for this manuscript was fully handled by G. Y. H. Lip, Editor in Chief.
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