Importance of viral and bacterial infections in chronic obstructive pulmonary disease exacerbations

G De Serres, N Lampron, J La Forge, I Rouleau… - Journal of Clinical …, 2009 - Elsevier
BACKGROUND: Few studies have evaluated the contribution of both viruses and bacteria in
acute exacerbation of chronic obstructive pulmonary disease (AECOPD). OBJECTIVES: This
study estimated the burden of both types of pathogens among adults seeking care for an
AECOPD during two consecutive winter seasons. STUDY DESIGN: Patients 50 years or
older who consulted within 10 days of AECOPD onset were eligible. Clinical data were
collected on a standardized questionnaire, and nasopharyngeal aspirates (NPA), paired …