Helicobacter pylori is a gastric pathogen that is present in half of the global population and is
a significant cause of morbidity and mortality in humans. Several mouse models of gastric
Helicobacter infection have been developed to study the molecular and cellular
mechanisms whereby H. pylori bacteria colonize the stomach of human hosts and cause
disease. Herein, we describe protocols to: 1) prepare bacterial suspensions for the in vivo
infection of mice via intragastric gavage; 2) determine bacterial colonization levels in mouse …